Extending the Minority Stress Model of Autism: Internalized Stigma and Loneliness as Predictors of Stress and Life Satisfaction.
Asselt Alvin van, Roke Yvette, Begeer Sander, Scheeren Anke M
What this study means for families
This study looked at how negative beliefs about autism and feelings of loneliness affect stress and happiness in 831 autistic adults. Researchers found that when autistic people internalize stigma about autism and feel lonely, they experience more stress and lower life satisfaction. The loneliness partly explained why negative beliefs about autism led to worse outcomes.
Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.
Research summary
This cross-sectional study examined minority stress processes in 831 autistic adults from the Netherlands Autism Register using the Psychological Mediation Framework. Participants (ages 18-87) completed self-report surveys measuring internalized autism-related stigma, loneliness, stress, and life satisfaction. Multiple regression analyses revealed that internalized stigma, emotional loneliness, and social loneliness were each positively associated with stress and negatively associated with life satisfaction. Mediation analyses demonstrated that both types of loneliness partially mediated the relationship between internalized stigma and these outcomes, supporting the framework's propositions about how minority stressors affect autistic adults' wellbeing.
Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.
Key findings
- 1
Internalized autism-related stigma was positively associated with stress and negatively associated with life satisfaction
Confidence: moderateRelevance: Suggests addressing internalized stigma may improve autistic adults' wellbeing - 2
Both emotional and social loneliness were associated with higher stress and lower life satisfaction
Confidence: moderateRelevance: Indicates importance of addressing loneliness in autistic adults - 3
Loneliness partially mediated the relationship between internalized stigma and adverse outcomes
Confidence: moderateRelevance: Suggests loneliness may be a key pathway through which stigma affects wellbeing
Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.
Clinical implications
Results suggest interventions targeting internalized stigma and loneliness may improve stress and life satisfaction in autistic adults. Clinicians should assess for internalized stigma and address social isolation. Support programs should focus on reducing minority stressors and building social connections.
Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.
Limitations
Cross-sectional design prevents causal inferences. Self-report measures may introduce bias. Sample limited to Netherlands Autism Register participants, potentially affecting generalizability. No control group comparison provided.
Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.
Original abstract
Autistic people's minority status makes them more vulnerable to minority stressors, such as stigmatization and victimization, which are linked to greater stress and lower life satisfaction. The Psychological Mediation Framework (PMF) proposes that cognitive, affective, and social-psychological processes help explain the relationships between these stressors and adverse outcomes. This cross-sectional study tested the PMF in autistic adults by examining how two of its key processes, internalized stigma and loneliness, are associated with stress and life satisfaction. Using self-report survey data from 831 autistic participants enrolled in the Netherlands Autism Register (NAR), aged 18-87 years ( = 47.5; = 12.5; 408 women, 309 men, and 114 gender-diverse individuals), multiple regression analyses showed that internalized autism-related stigma, emotional loneliness, and social loneliness were each positively associated with stress and negatively associated with life satisfaction.
Mediation analyses indicated that both types of loneliness partially mediated the relationship between internalized autism-related stigma and these outcomes. Supporting the PMF, the findings suggest that autism-related stigmas may become internalized and be associated with loneliness, which is linked to greater stress and lower life satisfaction. Future studies should build upon the PMF and explore strategies to mitigate underlying minority stressors.Lay AbstractAutistic adults often experience higher levels of stress and lower life satisfaction than non-autistic adults. Recently, research has suggested that these experiences are linked to them being part of a minority group-autistic people.
Minorities often experience extra stress from experiences like stigma, sometimes called minority stressors. A theoretical model, the Psychological Mediation Framework (PMF), describes how minority stressors are linked to differences in people's thoughts, emotions, and feelings. This study examined whether the PMF can also help explain the stress and life satisfaction of autistic adults. We did this by testing whether two important parts of the PMF, internalized autism-related stigma (negative beliefs about being autistic) and loneliness, were linked to their stress and life satisfaction (how content people feel with their lives overall).We analyzed data from 831 autistic adults who filled out a survey.
In our statistical models (mathematical analyses that test how variables are related), we took into account other factors that are more commonly used to examine which factors were statistically associated with stress and life satisfaction in autistic adults, such as the level of characteristics related to autism and education level. By doing this, we increased the chance that any relationships we found could be attributed to minority stressors.Autistic adults who experienced more internalized autism-related stigma, emotional loneliness (feeling disconnected from close relationships), and social loneliness (lacking a broader social network) reported higher stress levels and lower life satisfaction. We also found that autistic adults with more internalized stigma felt lonelier, and this loneliness was linked to higher stress and lower life satisfaction.The results suggest that autistic adults may internalize autism-related stigmas, which are linked to greater loneliness, higher stress, and lower life satisfaction. As these findings align with the PMF, we believe future studies should continue using this model.
Also, we recommend that researchers should study ways to reduce minority stressors and improve the mental health of autistic adults.
Evidence Grade
limited
Grade assigned by AutismInsights based on study type and published abstract.
Study Details
- Journal
- Autism : the international journal of research and practice
- Year
- 2026
- PMID
- 42100952
- DOI
- 10.1177/13623613261446876
MeSH Terms