[Hyperbaric oxygen therapy (HBOT) in the treatment of autism spectrum disorders].

This review looks at hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) as a possible treatment for autism. Some studies suggest it might help with speech, communication, and social skills. However, results vary between studies, and there can be side effects like ear damage or oxygen poisoning. More research is needed to understand if this treatment is safe and effective.

This review examines hyperbaric oxygen therapy (HBOT) as a complementary treatment for autism spectrum disorders (ASD). The authors propose that HBOT's potential mechanisms include anti-inflammatory effects, modulation of neuroplasticity, and impact on oxidative stress. Current research suggests HBOT may improve speech, communication, and psychosocial functioning in individuals with ASD. However, the review notes that results are often inconsistent, and potential adverse effects include barotrauma and oxygen toxicity.

The analysis covers experimental studies from 2012-2025, highlighting both potential benefits and safety concerns of this intervention approach.

HBOT shows potential for improving communication and social functioning in ASD, but inconsistent results and safety concerns limit clinical recommendations. The risk-benefit profile requires careful consideration, and HBOT should only be considered as a complementary therapy under medical supervision with appropriate safety monitoring.

The review acknowledges inconsistent results across studies. No specific methodology details, sample sizes, or quality assessments of reviewed studies are provided. The abstract does not specify the number of studies reviewed or their methodological rigor.

Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders whose etiology involves complex interactions of environmental, genetic, and neurobiological factors. The developing knowledge regarding the genesis of this disorder, along with the increasing number of diagnosed cases, creates a need to search for more effective treatment methods. One potential complementary therapy is hyperbaric oxygen therapy (HBOT). Its potential mechanism of action in ASD is primarily associated with its anti-inflammatory effects, modulation of neuroplasticity, and a potential impact on oxidative stress levels.

Current research shows that HBOT may improve certain behavioral and cognitive factors in individuals with ASD, such as speech, communication, and psychosocial functioning. However, these results are often inconsistent due to potential adverse effects of HBOT, such as barotrauma and oxygen toxicity. This article highlights the significance of HBOT in ASD based on available literature from experimental studies conducted between 2012 and 2025.