[Research progress on mechanisms and clinical management of comorbid constipation in children with autism spectrum disorder].

This review looks at constipation in autistic children, which is very common. The study suggests that when constipation gets worse, autism symptoms may also get worse. When constipation improves, autism symptoms might improve too. Doctors don't fully understand why this happens, but they can help by using different treatments like medications, diet changes, and other therapies tailored to each child.

This Chinese review examines the relationship between autism spectrum disorder (ASD) and constipation, the most common gastrointestinal issue in autistic children. The authors note that constipation severity correlates with ASD core symptoms, and that improving constipation may help alleviate these symptoms. The review covers assessment approaches and treatment options including pharmacological therapy, dietary interventions, gut microbiota modulation, and complementary medicine. While the mechanisms underlying this comorbidity remain unclear, the authors emphasize multidisciplinary assessment as fundamental to clinical management and advocate for personalized treatment approaches.

Supports multidisciplinary assessment and personalized treatment approaches for constipation in autistic children. Suggests that addressing gastrointestinal issues may be an important component of comprehensive autism care, potentially improving both physical and behavioral symptoms.

This is a narrative review without systematic methodology. The mechanisms underlying the ASD-constipation relationship remain unclear. No specific sample sizes, intervention details, or outcome measures are provided in the abstract.

Children with autism spectrum disorder (ASD) frequently have comorbid gastrointestinal problems, with constipation being the most prevalent. The onset and severity of constipation are closely related to the core symptoms of ASD, and improving constipation can alleviate these core symptoms. However, the mechanisms underlying comorbid constipation in ASD remain unclear. Multidisciplinary assessment is the foundation of clinical management for comorbid constipation in ASD.

Targeted pharmacological therapy, dietary interventions, gut microbiota modulation, and complementary and alternative medicine interventions can be chosen for personalized treatment. This review summarizes the mechanisms, assessment, and clinical management of comorbid constipation in ASD and aims to provide a reference for comprehensive interventions in ASD.