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Feeding difficulties, eating disorders and therapeutic approaches in autism spectrum disorder: An overview.

Pharmacological research2025

Siracusano Martina, Arturi Lucrezia, Riccioni Assia, Medoro Alessandro, Savino Rosa, Scapagnini Giovanni, Davinelli Sergio, Mazzone Luigi

What this study means for families

This review looks at eating and feeding problems in autistic children, which are very common. Many autistic children have trouble moving to solid foods, eat a limited variety of foods, and don't like trying new foods. They may also have stomach problems. These eating issues are connected to how autistic children process sensations and their need for routines to stay the same. The review examines different treatment approaches including medications, therapy, and nutrition strategies.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This 2025 review examines feeding difficulties in autism spectrum disorder (ASD), which are highly prevalent from early development. The authors identify key challenges including difficulty transitioning to solid foods, limited dietary variety, food neophobia, and associated gastrointestinal disorders. The review highlights that feeding problems in ASD are primarily linked to aberrant sensory processing and insistence on sameness - core autistic traits. Additionally, increased gastrointestinal disorders and altered gut microbiome composition in ASD individuals present additional therapeutic considerations.

The review aims to summarize evidence-based therapeutic approaches across pharmacological, psychological, and nutritional domains, though specific findings and recommendations are not detailed in the abstract.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    Feeding problems are highly prevalent in individuals with ASD from early developmental stages

    Confidence: moderateRelevance: Establishes feeding difficulties as a common concern requiring early identification and intervention
  • 2

    Primary clinical link between atypical eating behaviors and core autistic symptoms involves aberrant sensory processing and insistence on sameness

    Confidence: moderateRelevance: Provides theoretical framework for understanding feeding difficulties and designing targeted interventions
  • 3

    Increased risk of gastrointestinal disorders and altered gut microbiome composition in ASD individuals

    Confidence: moderateRelevance: Highlights need for comprehensive medical assessment and potential for microbiome-targeted interventions

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Feeding difficulties in ASD require multi-domain intervention approaches addressing sensory processing, behavioral rigidity, and gastrointestinal health. Early identification and intervention are important given the prevalence from early development. Treatment should consider pharmacological, psychological, and nutritional strategies tailored to individual sensory and behavioral profiles.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

As this is a review overview, specific methodological details, sample characteristics, and detailed findings are not provided in the abstract. The evidence quality of included studies and strength of recommendations cannot be assessed from the available information.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

Feeding problems are highly prevalent in individuals with autism spectrum disorder (ASD) from early developmental stages. Difficulties during the transition to solid foods, limited dietary variety, and reluctance to try new foods since infancy, combined with gastrointestinal disorders, represent significant concerns for both parents and clinicians from diagnostic and, more importantly, therapeutic perspectives. The primary clinical link between atypical eating behaviors and core autistic symptoms lies in aberrant sensory processing and an insistence on sameness, which have important implications for intervention strategies. Additionally, the increased risk of gastrointestinal disorders and altered gut microbiome composition in individuals with ASD constitute another critical factor, opening avenues for novel therapeutic approaches.

Therefore, the aim of this review is to summarize the existing literature on therapeutic approaches for feeding problems in ASD, with a focus on evidence-based practices across pharmacological, psychological, and nutritional domains.

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Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Type
Review
Journal
Pharmacological research
Year
2025
PMID
41260531
DOI
10.1016/j.phrs.2025.108040

MeSH Terms

HumansAutism Spectrum DisorderFeeding and Eating DisordersAnimalsFeeding BehaviorGastrointestinal Microbiome