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Dynamics of a novel fractional-order model for autism spectrum disorder perspective propagation with optimal control.

Scientific reports2025

Gumus Mehmet, Teklu Shewafera Wondimagegnhu

What this study means for families

Researchers created a mathematical model to study how negative attitudes about autism spread in society. They found that combining therapy programs with media awareness campaigns works best to change these attitudes - achieving a 75% improvement. Therapy alone was three times better than just media campaigns. The study shows that changing people's minds about autism takes time because past experiences strongly influence current views.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This mathematical modeling study developed a fractional-order model to understand how negative societal attitudes toward autism spread and persist over time. The model incorporates memory effects, showing that historical experiences continuously influence current perceptions. The study compared different intervention strategies, finding that therapeutic programs were three times more effective than media campaigns alone for changing negative attitudes. Combined interventions (media + therapy) achieved a 75% reduction in negative perspectives and were deemed cost-effective.

The fractional-order approach revealed that attitude changes occur 30-50% slower than predicted by traditional models, highlighting the persistent nature of social attitudes.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    Therapeutic interventions were three times more effective than media campaigns alone in changing negative perspectives toward autism

    Confidence: moderateRelevance: High - suggests prioritizing therapeutic approaches in public health interventions
  • 2

    Combined media and therapeutic interventions achieved 75% reduction in negative perspectives

    Confidence: moderateRelevance: High - demonstrates effectiveness of integrated intervention strategies
  • 3

    Attitude transitions occur 30-50% slower than predicted by traditional models due to memory effects

    Confidence: moderateRelevance: Moderate - informs realistic timelines for attitude change interventions

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Results suggest that sustained, combined interventions targeting both media representation and direct therapeutic engagement may be most effective for reducing autism stigma. The slower attitude change rates identified indicate that long-term commitment and realistic timelines are essential for successful stigma reduction programs.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

This is a theoretical mathematical modeling study without real-world validation. No actual participants or empirical data collection was involved. The model's assumptions and parameters may not accurately reflect complex real-world social dynamics and individual differences in attitude formation.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

This study addresses the propagation of negative societal perspectives toward Autism Spectrum Disorder (ASD) through a novel fractional-order mathematical model that captures the critical memory effect in individuals' attitude formation, where historical experiences continuously shape current perceptions. By analyzing intervention strategies combining media awareness campaigns and therapeutic programs, we demonstrate that fractional calculus reveals significantly slower attitude transitions (30-50 percent reduction in rate) compared to classical models, with therapeutic interventions proving three times more effective than media campaigns alone in rehabilitating negative perspectives of individuals. Our optimal control problem identifies a strategy that achieves a 75 percent reduction in negative perspectives, while cost-effectiveness analysis confirms the economic viability of the proposed combined approaches. These findings suggest that integrated interventions utilizing both media and therapy control measures yield the most efficient path to mitigating negative perspectives towards Autism Spectrum Disorder, with fractional-order modeling providing essential insights into the persistent nature of social attitudes that traditional integer-order models cannot capture.

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Evidence Grade

Emerging

emerging

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
Scientific reports
Year
2025
PMID
41238632
DOI
10.1038/s41598-025-23525-7

MeSH Terms

Autism Spectrum DisorderHumansModels, TheoreticalCost-Benefit Analysis