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Sociodemographic, clinical, and global functioning vulnerabilities in Mexican children and adolescents with and without autism spectrum disorders.

International review of psychiatry (Abingdon, England)2025

de la Peña Francisco R, Ulloa Rosa Elena, Rosetti Marcos F, Díaz Sánchez Ricardo, Soto-Briseño Alejandro Irvin, Mayer-Villa Pablo Adolfo, Escamilla-Orozco Raúl Iván, Medina-Rodríguez José Carlos

What this study means for families

This study looked at 22 Mexican children and teens with autism compared to 81 without autism. Children with autism were more likely to need special education and had lower overall functioning in daily activities. The researchers found that some children with autism had additional mental health challenges that made things even harder for them. This shows that autism affects children differently and some may need extra support.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This cross-sectional study compared sociodemographic, clinical, and functioning profiles between 22 Mexican children/adolescents with ASD and 81 without ASD at two Mexico City outpatient facilities. Using semi-structured interviews and standardized assessments, researchers found that participants with ASD had significantly higher rates of special education placement and lower global functioning scores on both the Children's Global Assessment Scale and WHO Disability Assessment Schedule 2.0. Those without ASD showed more oppositional/defiant symptoms. Latent class analysis identified a vulnerable subgroup within the ASD cohort characterized by increased psychosocial and psychopathological symptoms alongside reduced functionality, highlighting the heterogeneity within ASD presentations in Mexican youth.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    Children with ASD had significantly higher rates of special education placement compared to those without ASD

    Confidence: moderateRelevance: Indicates educational support needs in Mexican ASD population
  • 2

    ASD group showed significantly lower global functioning on standardized measures (CGAS and WHODAS 2.0)

    Confidence: moderateRelevance: Demonstrates measurable functional impairments requiring intervention
  • 3

    A vulnerable subgroup within ASD was identified with increased psychosocial symptoms and lower functionality

    Confidence: limitedRelevance: Suggests need for individualized assessment and support strategies

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Mexican children with ASD require comprehensive functional assessments and educational support planning. Clinicians should screen for co-occurring psychosocial symptoms to identify those at higher vulnerability. Findings support need for culturally relevant ASD services in Mexico and highlight importance of individualized intervention approaches.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

Small ASD sample size (n=22) limits generalizability. Cross-sectional design prevents causal inferences. Study limited to two Mexico City institutions may not represent broader Mexican population. Unknown study methodology details affect interpretation of findings.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

Research indicates that sociodemographic, clinical, and global functioning are associated with autism spectrum disorder (ASD). To measure and compare sociodemographic, clinical, and global functioning vulnerability profiles of a sample of Mexican children and adolescents with and without ASD. The study was done at two outpatient institutions in Mexico City. The assessment used semi-structured interviews with rating scales, and-tests and chi-squared () tests were run to evaluate group comparisons.

A latent class analysis was executed to generate probabilistic vulnerability profiles. A total of 103 participants were recruited, 22 with ASD (21.3%, mean age 12.8 ± 3.17, 77.27% male). Those without ASD showed a significantly special education placement (= 3.91, = 0.048), had oppositional and defiant symptoms ( = 3.32, = 0.001), and lower global functioning as measured by the Children's Global Assessment Scale ( = 11.78; = 0.001) and the World Health Organization Disability Assessment Schedule 2.0 ( = -4.10; = 0.001). Vulnerability was identified in a subgroup of participants with ASD due to increased psychosocial and psychopathological symptoms and lower global functionality.

Mexican children and adolescents with ASD experience special education placement and impaired global functioning.

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Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
International review of psychiatry (Abingdon, England)
Year
2025
PMID
41211729
DOI
10.1080/09540261.2025.2581849

MeSH Terms

HumansAutism Spectrum DisorderMexicoMaleChildAdolescentFemaleEducation, Special