Short Research Article: Autism spectrum disorder and gender dysphoria among adolescents in a large, integrated health system.

This study looked at the connection between autism and gender dysphoria (when someone's gender identity differs from their birth sex) in teenagers. It confirmed that autistic teens are more likely to experience gender dysphoria. The research also found that teens with both autism and gender dysphoria had higher rates of depression, anxiety, and thoughts of suicide. This highlights the importance of thorough assessments to provide the best support.

This cross-sectional study examined the relationship between autism spectrum disorder (ASD) and gender dysphoria (GD) among adolescents in a large, nonacademic civilian health system. The research validated previous findings of a positive association between ASD and GD that had been observed in academic medical centers and military settings. Importantly, the study found that adolescents with both diagnoses had higher rates of co-occurring mental health conditions, specifically depression, anxiety, and suicidality. The authors emphasize the need for comprehensive developmental and gender assessments to ensure optimal care for this population.

Clinicians should be aware of potential co-occurrence of ASD and gender dysphoria. Comprehensive assessments addressing both developmental and gender identity aspects are recommended. Enhanced mental health screening and support may be needed for individuals with both conditions.

Sample size not reported. Cross-sectional design prevents causal inferences. Limited details about methodology, participant characteristics, or control measures provided in the abstract.

The association between autism spectrum disorder (ASD) and gender dysphoria (GD) in youth has been suggested. Recent research among academic medical centers and the military health system has found a positive association, while not yet being sufficiently explored in a civilian, nonacademic community setting. We conducted a cross-sectional study among one of the largest nonacademic civilian databases within a single health system. This study validates the positive association between ASD and GD and finds that those with both diagnoses have a higher co-occurrence of depression, anxiety, and suicidality.

This emphasizes the need for comprehensive gender and developmental assessments to ensure optimal care.