Association between premenstrual syndrome or premenstrual dysphoric disorder and presence of ASD or ADHD among adolescent females: a retrospective study.

This study looked at how premenstrual symptoms relate to autism and ADHD in teenage girls. Researchers found that girls with ADHD were more likely to experience moderate to severe premenstrual problems. The effect was even stronger for girls who had both autism and ADHD together. Girls with only autism didn't show this increased risk. This suggests teenage girls with ADHD may need extra support around their menstrual cycle.

This retrospective study examined the relationship between premenstrual syndrome (PMS)/premenstrual dysphoric disorder (PMDD) and autism spectrum disorder (ASD) or ADHD in 290 adolescent females aged 10-19 years. Using standardized assessment tools including the QIDS, Autism-Spectrum Quotient, and PMDD assessment scale, researchers found significant associations between moderate to severe PMS and ADHD (OR: 2.43) and comorbid ASD + ADHD (OR: 3.27). Notably, ASD alone showed no significant association with PMS severity. The findings suggest females with ADHD, particularly those with comorbid ASD + ADHD, experience heightened vulnerability to premenstrual psychological distress, highlighting the need for early detection, intervention, and tailored treatment approaches for this population.

Clinicians should screen for premenstrual symptoms in adolescent females with ADHD, particularly those with comorbid ASD. Early identification and tailored interventions may help address heightened vulnerability to premenstrual psychological distress in this population. Treatment planning should consider menstrual cycle impacts on mental health.

Retrospective design limits causal inference. Sample characteristics and recruitment methods not fully described. Standardized tools used but validation in neurodivergent populations unclear. Cross-sectional analysis cannot establish temporal relationships between conditions.

This retrospective study aimed to investigate the association between premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) and the presence of autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) in adolescent females. While PMS and PMDD are well-studied in the general population, limited research exists on their prevalence and impact in adolescent females with ASD or ADHD. Retrospective data collection was conducted using electronic medical records, covering 290 patients aged 10-19 years. PMS severity, depressive symptoms, and autistic tendencies were assessed using standardized tools, including the Quick Inventory of Depressive Symptomatology (QIDS) for depressive symptoms, Autism-Spectrum Quotient (AQ) for autistic tendencies, and a PMDD assessment scale for PMS severity.

The results revealed a significant association between moderate to severe PMS and ADHD (odds ratio [OR]: 2.43) as well as comorbid ASD + ADHD (OR: 3.27). In contrast, ASD alone did not exhibit a significant link to PMS severity. These findings highlight the heightened vulnerability of females with ADHD or comorbid ASD + ADHD to premenstrual psychological distress, emphasizing the importance of early detection and intervention. The study underscores the need for tailored treatment strategies addressing the unique challenges faced by this population.