Advancements in Nanotechnology for Autism Spectrum Disorder: Innovative Strategies in Pediatric Neurology.

This review looks at how tiny technology called nanotechnology might help treat autism in children. The researchers discuss special delivery systems for medicines, sensors that could detect autism early, and gene therapy using very small particles. The goal is to create treatments that work better with fewer side effects, customized for each child's unique brain patterns.

This 2025 review examines the potential of nanotechnology applications in autism spectrum disorder treatment within pediatric neurology. The authors explore nanoscale interventions including targeted drug delivery systems to enhance therapeutic efficacy, nanosensors for early ASD detection, and nanocarriers for gene therapy approaches. The review emphasizes minimizing treatment side effects while maximizing benefits through personalized medicine approaches tailored to individual neurobiological profiles. The authors advocate for interdisciplinary collaboration and call for further research to validate these innovative nanotechnology strategies in clinical practice for pediatric autism care.

These nanotechnology applications remain largely theoretical and require extensive research before clinical implementation. While promising for personalized autism treatment, safety and efficacy must be established through rigorous clinical trials before considering real-world application in pediatric populations.

This is a narrative review without systematic methodology or specific studies analyzed. No empirical data, sample sizes, or clinical trial results are reported. The findings represent theoretical potential rather than proven clinical applications.

Autism spectrum disorder (ASD) presents significant challenges in pediatric neurology, necessitating innovative management strategies to improve outcomes for affected children. This review explores the transformative potential of nanotechnology in autism treatment, highlighting specific applications of nanoscale materials and devices. We provide a detailed examination of various nanotechnology-based interventions, including targeted drug delivery systems that boost therapeutic efficacy, nanosensors for the early detection of ASD, and nanocarriers designed for gene therapy, all aimed at minimizing side effects while maximizing treatment benefits. Additionally, we discuss the role of nanotechnology in developing personalized medicine approaches tailored to the unique neurobiological profiles of children with ASD.

By bridging the gap between research and clinical practice, this review aims to enhance the quality of care and life for pediatric patients with autism. We underscore the importance of interdisciplinary collaboration in advancing nanotechnology solutions and call for further research to validate these innovative strategies in pediatric neurology.