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The Impact of Face Mask Use on Research Evaluations of 5-7 Year-Old Children With Autism Spectrum Disorder.

Journal of autism and developmental disorders2026

Peisch Virginia, DePillis Rafael, Hanson Ellen, Brewster Stephanie J, Sideridis Georgios, Barbaresi William J, Harstad Elizabeth

What this study means for families

Researchers looked at how wearing face masks during COVID-19 affected autism assessments in 60 children aged 5-7. Most children (67%) could wear masks the whole time, 22% wore them sometimes, and 12% couldn't wear them. Children who couldn't wear masks had lower thinking and communication skills. However, researchers said mask-wearing didn't affect their ability to properly assess the children in 88% of cases.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This study examined how face mask use during COVID-19 affected autism research evaluations in 60 children aged 5-7 years with autism spectrum disorder. Two-thirds of children tolerated masks throughout assessments, while 22% wore them part-time and 12% couldn't tolerate them at all. Children who couldn't wear masks had significantly lower cognitive and communication scores compared to those who could. Importantly, research staff reported that mask use had no impact on assessment results in 88% of cases, suggesting that diagnostic evaluations remained reliable despite pandemic restrictions.

The findings indicate that most children with autism can accommodate mask-wearing during clinical assessments without compromising evaluation quality.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    66.7% of children with autism tolerated face masks throughout research assessments, 21.6% tolerated them part-time, and 11.6% could not tolerate them

    Confidence: moderateRelevance: Helps clinicians understand mask tolerance patterns and plan assessments accordingly
  • 2

    Children who could not tolerate masks had significantly lower cognitive and communication scores

    Confidence: moderateRelevance: Suggests mask intolerance may be associated with greater support needs
  • 3

    Research staff reported mask use had no impact on assessment results in 88% of cases

    Confidence: moderateRelevance: Supports continued use of standard assessment protocols during mask-wearing periods

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Most children with autism can successfully participate in clinical assessments while wearing masks. Clinicians should be prepared with alternative strategies for children who cannot tolerate masks, particularly those with lower cognitive and communication abilities. Assessment validity appears largely uncompromised by mask requirements.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

Small sample size (n=60) limits generalizability. Study relies on subjective researcher ratings rather than objective outcome measures. No comparison group without masks. Limited details about assessment protocols or mask accommodation strategies.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

The COVID-19 pandemic changed the nature of clinical research assessments. Little is known about the impact of face mask use on research assessments for autism spectrum disorder (ASD). This study reports on tolerability of face mask use, child characteristics associated with tolerability, and the impact of face mask use on researcher ASD diagnostic certainty ratings. This paper describes results from a larger study of children who were clinically diagnosed with ASD in early childhood and were re-evaluated at age 5-7 years.

Research diagnostic evaluations were conducted from 2018 to 2022 and included cognitive, language, and social-communication assessment. A research psychologist completed a rating scale on the potential impact of face mask use on research assessment diagnostic certainty for a subset of participants (n = 60) who were evaluated during the COVID-19 pandemic. The mean age of study participants was 6.2 years. Face masks were tolerated throughout the assessment for 40 children (66.7%); part-time for 13 (21.6%); and not tolerated for 7 (11.6%).

Analysis of Variance (ANOVA) suggested that children who did not tolerate a face mask had significantly lower cognitive [F(2, 59) = 13.241, p < 0.001] and communication [F(2, 59) = 13.639, p < 0.001] scores compared to children who wore their mask for all or part of the visit. For 88% of research assessments, research staff indicated that face mask use had "no impact" on overall assessment results. Face mask use during clinical research assessment was not reported by research staff to significantly impact their ability to complete ASD evaluations.

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Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
Journal of autism and developmental disorders
Year
2026
PMID
39578315
DOI
10.1007/s10803-024-06633-7

MeSH Terms

HumansAutism Spectrum DisorderMasksMaleFemaleChild, PreschoolChildCOVID-19