AutismInsights
Back to research database
Emerging

Cervical Cancer Screening and Prevention Uptake in Females with Autism Spectrum Disorder.

Journal of autism and developmental disorders2026

Chen Yachin, Powers James, McDougle Christopher J, Zürcher Nicole R, Thom Robyn P

What this study means for families

This study looked at cervical cancer prevention in autistic girls and women. It found that many aren't getting important vaccines or screening tests. Only about half got the HPV vaccine that prevents cervical cancer, and only 38% of women got pap smears. Those with language difficulties or intellectual disabilities were less likely to receive these services. This puts autistic females at higher risk for cervical cancer.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This study examined cervical cancer prevention and screening uptake among 181 females with autism spectrum disorder aged 11-65 years through an online survey. Results showed suboptimal rates: 56% of adolescents and 47% of adults received at least one HPV vaccine dose, with only 41% and 34% respectively being fully vaccinated. Among adults eligible for screening, only 38% had received a pap smear. Language impairment was associated with lower HPV vaccination rates, while language impairment, intellectual disability, non-independent living, and lower education were linked to reduced pap smear uptake.

The findings highlight significant gaps in preventive healthcare access for autistic females, indicating increased vulnerability to cervical cancer.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    56% of adolescents and 47% of adults with ASD received at least one HPV vaccine dose

    Confidence: moderateRelevance: Indicates significant gaps in preventive healthcare access
  • 2

    Only 38% of eligible adult females received cervical cancer screening

    Confidence: moderateRelevance: Demonstrates substantial under-screening putting women at risk
  • 3

    Language impairment, intellectual disability, and lower education associated with reduced healthcare uptake

    Confidence: moderateRelevance: Identifies vulnerable subgroups requiring targeted support

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Results indicate urgent need for healthcare system improvements to support cervical cancer prevention in autistic females. Targeted interventions should address barriers for those with language impairments and intellectual disabilities. Healthcare providers need training on autism-informed care for reproductive health services.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

Single survey study with potential selection bias from clinical referral cohort. Sample size not clearly reported. Cross-sectional design prevents causal inference. Online survey format may exclude those with greater support needs or limited digital access.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

This study reports on uptake rates of cervical cancer prevention and screening in a clinically-referred cohort of adolescent and adult females with autism spectrum disorder (ASD). Females with ASD (11-65 years) were invited to participate in an online survey to report on uptake of the human papillomavirus (HPV) vaccination and cervical cancer screening. Participants also provided demographic and clinical information. Chi-square statistical analysis was utilized to examine the relationship between categorical variables and receipt of cervical cancer prevention and screening.

Forty-one out of 73 (56%) of adolescent (11-17 years) and 51/108 (47%) of adult (≥ 18 years) females with ASD reported having received at least one dose of the HPV vaccine. Only 30/73 (41%) and 37/108 (34%) of adolescents and adults respectively, were fully vaccinated (≥ 2 doses). Language impairment was the only clinical factor found to be associated with non-receipt of the HPV vaccine. Thirty-one out of 82 (38%) adult females (≥ 21 years) with ASD had received at least one pap smear.

Language impairment, intellectual disability, non-independent living, and lower level of education were all associated with not receiving a pap smear. Females with ASD are vulnerable to invasive cervical cancer disease due to low uptake rates of the HPV vaccine and routine pap smear screening.

View Original Paper

View original paperFull paper via publisher (may require subscription)

Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
Journal of autism and developmental disorders
Year
2026
PMID
39294385
DOI
10.1007/s10803-024-06565-2

MeSH Terms

HumansFemaleAutism Spectrum DisorderUterine Cervical NeoplasmsAdolescentAdultMiddle AgedChildPapillomavirus VaccinesEarly Detection of CancerYoung AdultAgedPapanicolaou TestPatient Acceptance of Health CarePapillomavirus Infections