Exercise Changes Gut Microbiota: A New Idea to Explain that Exercise Improves Autism.

This review looks at how exercise might help children with autism by changing gut bacteria. We know exercise can help autism symptoms, and we know gut bacteria affects the brain. However, there aren't many studies yet that look at how exercise changes gut bacteria specifically in people with autism. The researchers think this could be an important area for future research.

This narrative review explores the theoretical connection between exercise, gut microbiota changes, and autism spectrum disorder (ASD) improvements through the microbial gut-brain axis (MGBA). The authors examine three key areas: alterations in gut microbiota components in ASD and their relationship to pathophysiology, the relationship between exercise and gut microbiota changes, and exercise effects on gut microbiota in central nervous system disorders. While exercise interventions have shown benefits for ASD in previous studies, and gut microbiota abnormalities are linked to autism, the authors note there are currently few studies specifically investigating exercise interventions on gut microbiota in autism populations.

While promising theoretically, the gut microbiota-exercise connection in autism requires substantial research before clinical application. Clinicians should continue evidence-based exercise interventions for ASD while monitoring developments in microbiome research.

This is a narrative review without systematic methodology. The abstract contains incomplete information with missing text where specific microbiota are mentioned. No original data is presented, and the evidence synthesis approach is unclear.

The effect of exercise interventions on autism spectrum disorder (ASD) has been demonstrated in many studies, and the discovery of a bidirectional relationship between the gut microbiome (GM) and the central nervous system (CNS) has led to the concept of the microbial gut-brain axis (MGBA) and has linked the abnormal GM to a variety of neuropsychiatric disorders, autism being one of them. Research on improving the GM through exercise is also starting to come into focus. However, there are currently few studies on exercise intervention in the GM of autism. The purpose of this review was to find evidence to explore the possible potential effects of exercise to improve the behavior of individuals with autism in the MGBA in this treatment, as well as the potential of GM as an exercise treatment for autism.

We will explore (1) changes in GM components of ASD and their relationship to the pathophysiology of ASD; (2) the relationship between exercise and changes in GM components, and (3) the effect of exercise on GM in CNS disorders. Ultimately, we concluded that,,,, andmay be potential effectors through the MGBA network during exercise to ameliorate ASD targeting microbiotas. They deserve high attention in the follow-up studies.