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Use of a Best Practice Alert (BPA) to Increase Diversity Within a US-Based Autism Research Cohort.

Journal of autism and developmental disorders2023

Duhon Gabrielle F, Simon Andrea R, Limon Danica L, Ahmed Kelli L, Marzano Gabriela, Goin-Kochel Robin P

What this study means for families

Researchers tested a computer alert system to help recruit diverse families for autism research. The alerts worked better at regular pediatric clinics than specialty clinics, getting more interest from families with private insurance and non-white families. However, alerts for families with public insurance were often dismissed by doctors, suggesting some bias in who gets offered research opportunities.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This study evaluated the effectiveness of a best practice alert (BPA) system in recruiting diverse families into autism research. The researchers compared response outcomes between pediatric primary care practices serving diverse communities and subspecialty clinics. Results showed that primary care practices had higher rates of interest from families with private insurance (60.9% vs. 46.2%) and non-white patients (47.7% vs. 33.3%) compared to subspecialty clinics. However, alerts for patients with public insurance were more frequently dismissed at primary care practices (30.1% vs. 20.0%), suggesting potential selection bias among pediatricians in determining which families receive study information.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    Primary care practices had higher interest rates from privately insured patients (60.9% vs. 46.2%) compared to subspecialty clinics

    Confidence: moderateRelevance: Demonstrates potential of primary care settings for diverse research recruitment
  • 2

    Primary care practices showed higher interest rates from non-white patients (47.7% vs. 33.3%) than subspecialty clinics

    Confidence: moderateRelevance: Indicates primary care may be more effective for reaching underrepresented populations
  • 3

    Alerts for publicly insured patients were dismissed more often at primary care practices (30.1% vs. 20.0%)

    Confidence: moderateRelevance: Suggests potential bias in provider decisions about research participation offers

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Best practice alerts in primary care settings may improve recruitment of diverse families for autism research, but provider bias may limit access for some populations. Training and guidelines may be needed to ensure equitable research opportunity distribution.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

Sample size not reported. Study design unclear from abstract. Limited detail on alert implementation or provider training. Potential confounding factors not addressed. No information on actual enrollment outcomes or long-term effectiveness.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

We evaluated the success of a best practice alert (BPA) in recruiting underrepresented families into an autism spectrum disorder research cohort by comparing BPA-response outcomes (Interested, Declined, Enrolled, Dismissed) in pediatric primary care practices (TCPs) serving diverse communities with those of subspecialty clinics. Compared to subspecialty clinics, TCPs had higher proportions of Interested responses for patients with private insurance (60.9% vs. 46.2%), Dismissed responses for patients with public insurance (30.1% vs. 20.0%), and Interested responses for non-white patients (47.7% vs. 33.3%). A targeted BPA can help researchers access more diverse groups and improve equitable representation. However, select groups more often had their alert dismissed, suggesting possible selection bias among some pediatricians regarding who should receive information about study opportunities.

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Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
Journal of autism and developmental disorders
Year
2023
PMID
34997882
DOI
10.1007/s10803-021-05407-9

MeSH Terms

HumansChildElectronic Health RecordsAutistic DisorderAutism Spectrum DisorderPediatricians